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    1. Beauty
    2. Skincare

    Over 45? These are the 9 best serums to firm, smooth and boost glow, according to experts

    This one step could transform your skin

    Mica Ricketts's avatar
    By Mica Ricketts
    Last updated 31 March 2025 In Buying Guides

    When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works.

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    It’s inevitable that as we grow older our skin will change, which means inevitably so too do our products. And while there’s so much beauty in the laughter and smile lines that illustrate a life well lived, it’s natural to want to keep our skin as healthy as possible as it ages with us. Typically, skin tends to lose a lot of its natural elasticity and hydration over time—so choosing products that will help to support your skin’s collagen and moisture levels not only means that it will remain strong and healthy, but it will look brighter, smoother and firmer too. It’s a win-win. And while experts agree that bookending your skincare with a decent cleanser and a moisturiser for mature skin is really important, choosing the best serum for you might actually be the most important step in your routine. With that in mind, here is the Marie Claire guide to the best serums for mature skin.

    The best serums for mature skin: Quick links

    • Best serum for brightening mature skin: Beauty Pie YouthBomb 360° Radiance Concentrate Serum, £44 | Beauty Pie
    • Best beginner’s retinol serum for mature skin: CeraVe Resurfacing Retinol Serum, £23 | Sephora
    • Best plumping serum for mature skin: Dermalogica Pro-Collagen Banking Serum, £89 | Sephora
    • Best antioxidant serum for mature skin: Vichy Liftactiv Supreme 15% Pure Vitamin C Brightening Serum £42.50 | LookFantastic
    • Best serum for mature skin prone to sensitivity: Caudalie Resveratrol-Lift Instant Firming Serum, £52 | Sephora
    • Best serum for smoothing mature skin: Skin Design London Face Tight Serum, £205 | Harvey Nichols
    • Best serum for mature skin with hyperpigmentation: La Roche-Posay Mela B3 Anti-Dark Spot Serum, £48 | Cult Beauty
    • Best firming serum for mature skin: Elemis Pro-Collagen Future Restore Serum, £115 | Elemis
    • Best all-rounder serum for mature skin: Dr. Barbara Sturm Super Anti-Aging Serum, £290 | Dr. Barbara Sturm

    What do the best serums for mature skin actually do?

    “Serums are the powerhouses in your skincare routine that deliver lightweight, fast-absorbing, targeted actives directly to the skin,” explains skincare and clinical expert Fatma Shaheen, Founder and CEO of Skin Design London. “A serum is the product that addresses a specific skin concern—such as hyperpigmentation, fine lines and wrinkles, dehydration and lifting or firming the skin. They penetrate deeply to deliver potent ingredients in the most effective way.”

    Which ingredients should we look for in a serum for mature skin?

    “The most common concerns I see from clients are fine lines and wrinkles, loss of firmness and sagging skin, hyperpigmentation and sun damage, dryness and dehydration, and dullness and lack of glow,” explains Fatma. Quite the list. If you’re also looking to target some of these areas then there are specific ingredients to seek out which can really help.

    “For fine lines and pigmentation look for retinols or retinoids, for redness look for azelaic acid and for a brightening effect look for niacinamide,” explains Consultant Dermatologist Dr Sophie Momen. “Hyaluronic acid will add moisture to the skin and vitamin C or antioxidant serums are a great addition to a morning skincare routine to combat signs of ageing and pigmentation.”

    The 8 best serums for mature skin

    1. Beauty Pie YouthBomb 360° Radiance Concentrate Serum

    Mica Ricketts holding Beauty Pie YouthBomb 360° Radiance Concentrate Serum

    (Image credit: Mica Ricketts)

    Beauty Pie YouthBomb 360° Radiance Concentrate Serum

    (Image credit: Beauty Pie)

    Beauty Pie YouthBomb 360° Radiance Concentrate Serum

    Best serum for brightening mature skin

    Specifications

    Size: 50ml
    Key ingredients: Biolog-Elastic™ Complex including marine actives, hexapeptides and proteins
    Today's Best Deals
    £44 at Beauty Pie

    Reasons to buy

    +
    Seriously boosts glow
    +
    Improves overall skin texture

    Reasons to avoid

    -
    A great all-rounder, rather than targeting specific areas of concern

    Price shown is Beauty Pie member price.

    I’m a huge advocate of Beauty Pie as its direct-from-the-lab formulations are always seriously impressive, but at a fraction of the price of some of its competitors. This is one of the most expensive products that it's ever launched—the non-member price is £185—and it really does hold its own against some of the seriously expensive dermatologist skincare brands on the market. Created in collaboration with renowned Consultant Dermatologist Dr Andrew Markey, it aims to boost glow, smooth skin texture and tighten and brighten via a potent blend of 15 active ingredients—including marine actives for elasticity and firming, a synthetic hexapeptide to brighten and protect, and a moisturising phyto extract. Dr Markey claims it will “replicate the wow effect” that you can expect post-treatment at a dermatologist's office, and I can attest to the post-facial radiance that it delivers.

    2. CeraVe Resurfacing Retinol Serum

    CeraVe Resurfacing Retinol Serum

    (Image credit: CeraVe)

    CeraVe Resurfacing Retinol Serum

    Best beginner’s retinol serum for mature skin

    Specifications

    Size: 30ml
    Key ingredients: Encapsulated retinol, ceramides, niacinamide, liquorice root extract
    Today's Best Deals
    £23 at Sephora

    Reasons to buy

    +
    Exfoliates and smoothes without irritating the skin
    +
    Very affordable for a retinol

    Reasons to avoid

    -
    Best suited to those with scarred or textured skin

    Every time I talk to dermatologists and skin experts about the best ingredients for mature skin, retinol is always the one that comes out on top. However, retinol serums do need to be introduced with caution, and if you’re entirely new to using one then I’d recommend this as a great place to start—and Dr Sophie Momen suggests it as a brilliant evening serum for mature skin too. Formulated with an encapsulated retinol, this serum has been formulated with sensitive skin in mind to minimise risk of irritation and redness. Alongside all of the skin-smoothing and renewing benefits of the retinol itself, there’s also niacinamide to brighten, and the brand’s trademark ceramide blend to nourish and bolster the skin barrier. It’s particularly good if you had acne in your younger years and are still dealing with the scars, but it also helps to smooth over large pores and other texture for a more even complexion all-round. Start by using it once a week and then build up as your skin tolerates it.

    3. Dermalogica Pro-Collagen Banking Serum

    Mica Ricketts holding bottle of Dermalogica Pro-Collagen Banking Serum

    (Image credit: Mica Ricketts)

    Dermalogica Pro-Collagen Banking Serum

    (Image credit: Dermalogica)

    Dermalogica Pro-Collagen Banking Serum

    Best plumping serum for mature skin

    Specifications

    Size: 30ml
    Key ingredients: Collagen amino acids, jojoba ester, polyglutamic acid
    Today's Best Deals
    £89 at Sephora

    Reasons to buy

    +
    Plumps and firms skin long-term
    +
    Creates a really juicy, smooth complexion

    Reasons to avoid

    -
    It’s on the pricier side

    As we age our body starts to produce less collagen, which is why lack of firmness and elasticity is one of the first changes that we might notice in our skin as we grow older. I’m 35 now and can already attest to the fact that my skin feels so much thinner and less dense than it did five years ago. This innovative serum from Dermalogica aims to tackle that very concern using a science-backed blend of collagen, amino acids and Carnosine Dipeptide—a potent antioxidant—to hydrate and plump the skin in the short-term, but help your skin’s collagen levels to last longer for improved texture and tone in the long-term too. (Hence the ‘banking’ in the name.) It can be used morning and night to hydrate, plump and strengthen the skin barrier, and skin undoubtedly looks firmer, fuller and smoother with continued use.

    4. Vichy Liftactiv Vitamin C Brightening Skin Corrector Serum

    Vichy Liftactiv Vitamin C Brightening Skin Corrector Serum

    (Image credit: Vichy)

    Vichy Liftactiv Vitamin C Brightening Skin Corrector Serum

    Best antioxidant serum for mature skin

    Specifications

    Size: 20ml
    Key ingredients: 15% pure vitamin C
    Today's Best Deals
    £42.50 at Lookfantastic

    Reasons to buy

    +
    Protects against external aggressors
    +
    Brightens skin

    Reasons to avoid

    -
    The bottle is small, but it does mean the vitamin C remains potent

    Dr Sophie Momen recommends this as one of the best antioxidant serums to use in the morning for mature skin and it’s a great affordable alternative to another one of her favourites—the cult SkinCeuticals C E Ferulic .Formulated with 15% pure vitamin C, this serum is a real hard worker when it comes to protecting skin from external factors like pollution which can really cause our skin to become dull as we age. Instead, a morning dose of this acts like an antioxidant defence shield—brightening skin, boosting radiance and smoothing texture as it protects. The bottle is small, admittedly, but vitamin C loses potency once exposed to air so this means you’ll enjoy the product at its most active before you hit the bottom.

    5. Caudalie Resveratrol-Lift Instant Firming Serum

    Mica Ricketts holding Caudalie Resveratrol-Lift Instant Firming Serum

    (Image credit: Mica Ricketts)

    Caudalie Resveratrol-Lift Instant Firming Serum

    (Image credit: Caudalie)

    Caudalie Resveratrol-Lift Instant Firming Serum

    Best serum for mature skin prone to sensitivity

    Specifications

    Size: 30ml
    Key ingredients: Vegan collagen 1, hyaluronic acid, vine resveratro
    Today's Best Deals
    £52 at Sephora

    Reasons to buy

    +
    Gentle, non-irritating formula
    +
    For hydrated, smooth and dewy-looking skin

    Reasons to avoid

    -
    Not the most active formula

    This serum has been going viral on TikTok this year with fans of the product referring to it as a facelift in a bottle. Bold claims indeed, but in this instance I can see where they’re coming from. (And I’m not alone either—Marie Claire contributor Jazzria Harris also raves about the smoothing effects of this serum.) Unlike a lot of the serums on this list, I’d highly recommend this if you have sensitive skin that’s starting to see the effects of ageing—as it has none of the potentially irritating actives of some of the other formulas and is totally free from retinol. Instead, it uses something called Vegan Collagen 1—a plant-derived collagen combined with the brand’s patented anti-ageing complex of vine resveratrol, hyaluronic acids and a vegan collagen booster to improve the bounciness of skin, smooth fine lines and improve texture overall. The brand claim that this innovation makes it three times more effective than retinol based on studies, but whether or not that is the case, the visible results can’t be argued with. Skin is left smooth, dewy and plump with an almost glass-like shine with regular use, and no irritation in sight.

    6. Skin Design London Face Tight Serum

    Skin Design London Face Tight Serum

    (Image credit: Skin Design London)

    Skin Design London Face Tight Serum

    Best serum for smoothing mature skin

    Specifications

    Size: 30ml
    Key ingredients: Triple hexapeptide technology
    Today's Best Deals
    £205 at Harvey Nichols

    Reasons to buy

    +
    Dramatically reduces appearance of fine lines and wrinkles
    +
    Will look like you’ve just had a salon facial

    Reasons to avoid

    -
    It’s incredibly expensive

    With a lifetime of experience under her belt treating top-tier clients and working alongside dermatologists and doctors, it’s no surprise that award-winning skincare and clinical expert Fatma Shaheen’s skincare line is as impressive as the woman herself. Likened to botox in a bottle, her Face Tight serum lifts, tightens, smooths and rejuvenates the skin so you’ll look like you’ve just had a professional facial. Alongside peptides—which really are the building blocks of the skin—and some impressive cosmoceuticals to firm, it’s an expensive but effective choice if you’re looking to blur over more settled lines and wrinkles. And if you’re not convinced then the 5-star reviews really speak for themselves with one customer describing it as a “game-changer” that “visibly reduced fine lines”.

    7. La Roche-Posay Mela B3 Anti-Dark Spot Serum

    Mica Ricketts holding La Roche-Posay Mela B3 Anti-Dark Spot Serum

    (Image credit: Mica Ricketts)

    La Roche-Posay Mela B3 Anti-Dark Spot Serum

    (Image credit: La Roche-Posay)

    La Roche-Posay Mela B3 Anti-Dark Spot Serum

    Best serum for mature skin with hyperpigmentation

    Specifications

    Size: 30ml
    Key ingredients: Melasyl, 10% niacinamide, thermal spring water
    Today's Best Deals
    £48 at Sephora

    Reasons to buy

    +
    Reduces appearance of existing dark spots
    +
    Works to prevent new pigmentation forming

    Reasons to avoid

    -
    Contains retinol so use with an SPF

    One of the most impressive skincare launches of the last year in my opinion, La Roche-Posay’s latest serum is brilliant for anyone looking to target dark spots, discolouration or pigmentation—but is particularly suited to mature skin thanks to the complex formula that looks after skin health too. The active that gets to work on the hyperpigmentation is Melasyl, which not only minimises any existing discolouration but actually prevents new dark spots from forming. Plus, it is also brimming with niacinamide (10% in fact) and retinol to strengthen the skin barrier and encourage a faster cell turnover for stronger, brighter, healthier skin. I’ve had pigmentation post-pregnancy and this has really helped to fade its appearance.

    8. Elemis Pro-Collagen Future Restore Serum

    Elemis Pro-Collagen Future Restore Serum

    (Image credit: Elemis)

    Elemis Pro-Collagen Future Restore Serum

    Best firming serum for mature skin

    Specifications

    Size: 30ml
    Key ingredients: Opal skin algae complex, marine cellular lipids, marine bacillus ferment, padina pavonica ferment
    Today's Best Deals
    £115 at Elemis

    Reasons to buy

    +
    Improves skin firmness and texture
    +
    Boosts glow
    +
    Minimises appearance of wrinkles and fine lines

    Reasons to avoid

    -
    It's very expensive

    Elemis’s iconic Pro-Collagen products come up time and time again as some of the best skincare formulations for mature skin, and this expensive but efficacious serum is no exception. The product has undergone rigorous testing and is clinically proven to increase the firmness of skin by up to 46% in just 4 days—an astounding feat in itself. But that aside, it actually works long-term by targeting the effects of dwindling collagen in the skin and working to plump skin, improve its overall health, and boost brightness. Yes, it is an expensive option, but if you’ve got the money then it’s one of the best serums for mature skin if you’re looking for both short and long-term results.

    9. Dr. Barbara Sturm Super Anti-Aging Serum

    Dr. Barbara Sturm Super Anti Aging Serum

    (Image credit: Dr. Barbara Sturm)

    Dr. Barbara Sturm Super Anti-Aging Serum

    Best all-rounder serum for mature skin

    Specifications

    Size: 30ml
    Ingredients : Purslane Extract, Skullcap, Hyaluronic Acid, Glutathione
    Today's Best Deals
    £290 at Dr. Barbara Sturm

    Reasons to buy

    +
    Super hydrating
    +
    Calms irritation
    +
    Features active, powerhouse ingredients

    Reasons to avoid

    -
    It's pricey

    While Dr. Barbara Sturm products may be on the pricier end of the spectrum, they certainly pack a punch when it comes to their formulations. Skin loses moisture and collagen as it ages, meaning that we need to use super-charged topicals, and this serum delivers exactly that, thanks to a potent blend of active, high concentration ingredients known as Purslane and Skullcap, alongside antioxidants and weighted hyaluronic acid molecules. Described as an “anti-aging” cocktail, after just a few days of use, you will notice that fine lines and wrinkles look less pronounced, and that the skin feels nourished. This is great for sensitive skin too, and noticeably calms any irritation.

    Marie Claire Newsletter

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    Mica Ricketts
    Mica Ricketts
    Freelance Beauty Editor and Contributor

    Mica Ricketts is a freelance beauty editor and contributor to Marie Claire. She has written for titles including Refinery29 and Who What Wear UK, and also works with beauty brands on content messaging and marketing copy. She was previously Who What Wear UK's beauty editor. As someone that has tried basically every acne product on the market, she has a particular passion for debunking skincare myths and finding products that work. Plus, with two small children at home she is all about time-saving beauty routines that boost glow and disguise dark circles.

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