Marie Claire UK Marie Claire UK
  • Fashion Fashion
      • Fashion
        • View all Fashion
        • Fashion Trends
        • Shopping
        • Watches and Jewellery
        • Fashion News
  • Beauty Beauty
      • Beauty
        • View all Beauty
        • Fragrance
        • Hair
        • Make Up
        • Skincare
        • Nails
        • Marie Claire Beauty Awards
  • Health Health
      • Health
        • View all Health
        • Fitness
        • Nutrition
        • Female Health
        • Wellbeing
  • Life Life
      • Life
        • View all Life
        • Opinions
        • Travel
        • Sustainability
        • Weddings
        • Money & Work
        • Competitions
  • Culture Culture
      • Culture
        • View all Culture
        • TV and Film
        • Celebrity News
        • Books
        • Royal News
  • Vouchers Vouchers
      • Clothing
        • View all Vouchers
        • Mint Velvet
        • Karen Millen
        • H&M
        • nobody's child
        • ASOS
        • ARKET
        • MANGO
      • Designer Clothing
        • View all Vouchers
        • Reiss
        • THE OUTNET
        • SSENSE
        • Mytheresa
        • Liberty London
        • Selfridges
        • Farfetch
      • Accessories
        • View all Vouchers
        • AllSaints
        • Aspinal of London
        • Charles & Keith
        • River Island
        • FitFlop
        • Kate Spade
        • Vagabond
      • Jewellery
        • View all Vouchers
        • Pandora
        • Abbott Lyon
        • Goldsmiths
        • Beaverbrooks
        • Astrid & Miyu
        • Swarovski
        • Angara Jewellery
      • Beauty
        • View all Vouchers
        • Sephora
        • Cult Beauty
        • Space NK
        • Dyson
        • Clarins
        • Look Fantastic
        • Clinique
      • Activewear
        • View all Vouchers
        • Lululemon
        • Gymshark
        • Sweaty Betty
        • Nike
        • adidas
        • New Balance
        • Helly Hansen
  • NEWSLETTER Signup to our newsletter
  • logoCreated with Sketch.
    Marie Claire Newsletter

    Celebrity news, beauty, fashion advice, and fascinating features, delivered straight to your inbox!


    By submitting your information you agree to the Terms & Conditions and Privacy Policy and are aged 16 or over.

    You are now subscribed

    Your newsletter sign-up was successful


    An account already exists for this email address, please log in.
    Trending
    • Latest Issue
    • Marie Claire Masters
    • Autumn Winter 2026
    • Nail Trends 2026
    • Best Investment Bags
    • Best Perfumes
    1. Health and Fitness

    There's a genetic reason behind why you drink so much coffee

    Who knew?

    By Marie Claire
    Published 30 August 2016 In Features

    When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works.

    Coffee Is Good For You
    Coffee Is Good For You
    • Facebook
    • X
    • Pinterest
    Share this article
    Join the conversation
    Follow us
    Add us as a preferred source on Google
    Subscribe to our newsletter

    Who knew?

    Ever wondered why you need so much coffee to get through the day, while others are bright and breezy with barely an ounce of caffeine in their systems? It's all down to genetics.

    A recent study, published on nature.com, has found that the gene variation PDSS2 causes some people to metabolise coffee slower, and therefore need less of it. The gene is responsible for lowering caffeine cravings and the length of time it stays in your system for. Therefore, if you have it, you need less coffee than everyone else because the caffeine 'buzz' lasts longer.

    Those without the gene variation metabolise coffee at a normal (and fairly quick) pace, meaning that you've barely finished your first cup of the day before reaching for a second.

    Science never ceases to amaze us.

    You may like
    • A woman on the beach, in a bikini, eating some fruit I'm an Exercise Physiologist—If You’re Feeling Puffy, Tired, and Achy This Summer, These Everyday Habits Could Be Playing a Role
    • The moon in the sky, a sound bath, and a woman stretching I Did an ‘Energy Audit’ of My Entire Day—What Was Actually Draining Me is Shocking
    • Kirsten Dunst as Marie Antoinette surrounded by lavish luxury in Sofia Coppola’s film, illustrating why does nothing feel as good anymore. The Age of Underwhelm: Why Does Nothing Feel as Good as It Should?

    On 30th August, we wrote...

    We have a lot to thank coffee for – the majority of us rely heavily on it to wake us up in the morning or give us a boost throughout the day. We’ve previously reported on the health benefits of coffee drinking, such as how it could save your liver from booze, or even reduce your risk of developing MS.

    Marie Claire Newsletter

    Celebrity news, beauty, fashion advice, and fascinating features, delivered straight to your inbox!

    By submitting your information you agree to the Terms & Conditions and Privacy Policy and are aged 16 or over.

    Some people, however, don’t react well to coffee drinking, and it gives them the shakes or really bad headaches when they drink it. Sound familiar?

    Well if this is you, then it’s likely that your metabolism is to blame, according to author and wellness expert, Dr Michael Roizen of the Cleveland Clinic. Speaking to WJHG, he explained some of the side affects people experience if they’re more sensitive to caffeine.

    'If you have a normal cup of coffee that’s filtered, eight ounces, so you drink it within an hour, and you don’t get a headache, you don’t get abnormal heartbeats, you don’t get anxiety, you don’t get gastric upset, you’re most likely a fast metaboliser' he said.

    So, if you're one of those people who react badly when you drink a cup of coffee, however, it’s likely that you have a slow metabolism.

    Almost nine out of ten of us are 'fast metabolisers', and so get all the benefits of caffeine when we grab a Starbucks in the morning. It’s thought that caffeine can decrease the risk of Alzheimer’s, Parkinson’s, type 2 diabetes and even some forms of cancer. If you have bad reactions to coffee, though, the negative effects pretty much outweigh any possible long-term benefits. And so, it’s not really worth it.

    But most of us can keep happily drinking our Starbucks knowing that we have a fast metabolism and that we’re benefiting in the health department, too. Win-win.

    Marie Claire
    Social Links Navigation

    The leading destination for fashion, beauty, shopping and finger-on-the-pulse views on the latest issues. Marie Claire's travel content helps you delight in discovering new destinations around the globe, offering a unique – and sometimes unchartered – travel experience. From new hotel openings to the destinations tipped to take over our travel calendars, this iconic name has it covered.

    Read more
    A woman on the beach, in a bikini, eating some fruit
    Female health I'm an Exercise Physiologist—If You’re Feeling Puffy, Tired, and Achy This Summer, These Everyday Habits Could Be Playing a Role
    The moon in the sky, a sound bath, and a woman stretching
    Wellbeing I Did an ‘Energy Audit’ of My Entire Day—What Was Actually Draining Me is Shocking
     
     
    Kirsten Dunst as Marie Antoinette surrounded by lavish luxury in Sofia Coppola’s film, illustrating why does nothing feel as good anymore.
    Life The Age of Underwhelm: Why Does Nothing Feel as Good as It Should?
    A woman drinking a cup of tea in bed
    Health and Fitness 5 Everyday 'Life Admin' Habits That Are Secretly Exhausting You
     
     
    Latest in Health and Fitness
    Esmee Gummer finishing the Nation's 5k
    Fitness “I Was Told I Might Never Walk Again”: Esmée Gummer on Running 5,000km and Getting 1 Million People Moving
    A woman reading a book in bed; bedsheets and flowers
    Wellbeing Move Over, White Noise: New Research Says Pink Noise Can Clean Your Brain as You Sleep—Scientists Weigh In
     
     
    Roasted carrots, parsnips, and onions: A chopping board with vegetables on for chicken soup
    Nutrition My Grandmother Swore By Chicken Soup When We Were Ill—Our Experts Weigh In on Which Urban Wellness Legends Actually Work
    90's supermodel-turned-Nutritionist and Functional Medicine Practitioner Rosemary Ferguson
    Nutrition Forget the Crash Diet: The 4-Week Midlife Reset That’s About Feeling Better, Not Eating Less
     
     
    Latest in Features
    Are electric toothbrushes worth it?
    Beauty Is a £300 Electric Toothbrush Really Better Than a £30 One? We Asked Leading Dentists to Weigh In
    Actress Emilia Clarke
    Culture The Anti-Maxxing Issue: Featuring Emilia Clarke, Signature Scents, Practical Styling Tips and So Much More
     
     
    The best things to do this October
    Food and Drink The Agenda: Your October Just Got More Interesting
    A female worker in a garment factory in Dhakha, Bangladesh.
    Fashion The Human Cost Of Fashion’s Heat Crisis: “It Feels Like Being Locked Inside A Pressure Cooker At High Flame”
     
     
    logoCreated with Sketch.
    • Site Archive
    • Contact Future's experts
    • Contact us
    • Terms and conditions
    • Advertise with us
    • Privacy policy
    • Cookies policy
    • About us
    Add as a preferred source on Google Add as a preferred source on Google

    Marie Claire UK is part of Future plc, an international media group and leading digital publisher. Visit our corporate site.

    © Future Publishing Limited Quay House, The Ambury, Bath BA1 1UA. All rights reserved. England and Wales company registration number 2008885.